ARA-290 Neuroprotection Protocol

Recovery intermediate 1 compound NeuroprotectionPain ReliefTissue RepairAnti-Inflammation

A clinically-studied neuroprotective protocol using ARA-290 (Cibinetide) to target small fiber neuropathy, chronic inflammation, and tissue repair via the innate repair receptor (IRR).

Duration8 weeks

Break4 weeks

Full cycle12 weeks

Difficultyintermediate

Compounds1

01Compounds & dosing

ARA-290

Neuroprotection

Dose

2-4 mg/day (SubQ)

Frequency

Daily

Timing

Morning, subcutaneous injection

Start at 2mg and increase to 4mg as tolerated. Clinical trials used 4mg daily for 28 days with significant improvement in small fiber neuropathy.

Convert these to syringe unitsOpen the reconstitution calculator to turn any dose above into an exact draw on a U-100 insulin syringe.

02Weekly timeline

Week 1-2

Initial adaptation. Begin at 2mg daily. Subtle reduction in neuropathic symptoms.

Week 3-4

Increase to 4mg daily if tolerated. Measurable improvement in small fiber function. Reduced pain and tingling.

Week 5-6

Significant neuroprotective effects. Improved metabolic markers. Enhanced tissue repair.

Week 7-8

Peak neuroprotective benefits. Sustained nerve regeneration and pain relief.

03Who this is documented for

Individuals experiencing small fiber neuropathy, diabetic neuropathy, chronic inflammatory conditions, or those seeking neuroprotective support.

04Reported outcomes

Small fiber nerve regeneration,Neuropathic pain relief,Anti-inflammatory (non-immunosuppressive),Metabolic improvement (HbA1c reduction),Tissue repair via innate repair receptor

05Important notes

Start at 2mg daily, increase to 4mg after 2 weeks if tolerated,Half-life is approximately 2-3 hours — daily dosing is essential,Monitor neuropathy symptoms and report improvements to provider

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Research and educational use onlyNothing on this site is medical advice, a prescription, or a recommendation for human use. Compounds documented here are research chemicals. Consult a qualified clinician before making any health decision.